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KMID : 0363319900110020148
Journal of Korean Oriental Internal Medicine
1990 Volume.11 No. 2 p.148 ~ p.169
Effects of Soo Jeom San on the Functions of Heart and Digestive Organs
Lee Key-Sang

Moon Byung-Soon
Abstract
The Present experiment was designed to investigate the effects of Soo Jeom San on the function of heart and digestive organs. And thus it was analyzed the total acidity, recovery effect, and the other various enzyme activities such as ATPase, Creatine kinase, Aspartate transaminase, and Lactate dehydrogenase.
The results were obtained as follows :
1. The Total acidity decreased after Soo JeomSan administration for 6 days, however the total acidity inoreased after the drug administration for 9 days, these phenomena demonstrate that Soo Jeom San acts as a dual factor. The mechanism of decreasing the total acidity was considered to the inhibition of ATPase activity used for HCI active transport from parietal cells.
2. Soo Jeom San recovered the islets of Langerhans which was disrupted by streptozotocin. The recovery mechanism was suggested that Soo Jeom San stimulates the ¥â-cell proliferation.
3. Soo Jeom San inhibited the enzyme activities such as Creatine kinase and Aspartate transaminase, however the drug activated Lactate dehydrogenase.
According to the obtained results, Soo Jeom San may be used for curing gastric ulcer and myocardiac infarction.
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